Monday, March 30, 2026
Can a new psoriasis drug outperform an established treatment?
Photo by Charl Durand / Unsplash

Can a new psoriasis drug outperform an established treatment?

Plain Language Summary
What this means for you:
A new psoriasis drug was tested, but we don't yet know the results.

When you're living with the painful, itchy, and visible patches of moderate to severe plaque psoriasis, finding a treatment that works is everything. A new drug called bimekizumab has entered the scene, and researchers wanted to see if it could be a better option. In a major late-stage trial involving 567 adults, they directly compared bimekizumab to a placebo and to ustekinumab, a drug many patients already use.

The goal was to see if bimekizumab could help more people achieve very clear skin. The study measured two key things: the percentage of people who saw a 90% improvement in their psoriasis area and severity, and the percentage whose skin was rated as 'clear' or 'almost clear' by a doctor. However, the specific results—how many people actually hit these targets, and how bimekizumab stacked up against the other treatments—have not been released.

We also don't know about the drug's safety from this announcement. Every medication can have side effects, but the details on what, if any, adverse events occurred during the 13-month study period are not available. The trial was funded by the company that makes bimekizumab, which is standard but is always a factor to consider. For now, the core question of whether this new drug is more effective or safer remains unanswered until the full data is shared.

What this means for you:
A new psoriasis drug was tested, but we don't yet know the results.
Read the Full Clinical Summary →
View Original Abstract ↓
Status: COMPLETED | Phase: PHASE3 Condition(s): Chronic Plaque Psoriasis, Moderate to Severe Chronic Plaque Psoriasis, Psoriatic Arthritis Intervention(s): Bimekizumab (DRUG), Ustekinumab (DRUG), Placebo (OTHER) This is a study to compare the efficacy of bimekizumab versus placebo and an active comparator in the treatment of subjects with moderate to severe chronic plaque psoriasis (PSO). Primary Outcome(s): Percentage of Participants With a Psoriasis Area and Severity Index 90 (PASI90) Response at Week 16; Percentage of Participants With an Investigator's Global Assessment (IGA) (Clear or Almost Clear With at Least a 2-category Improvement From Baseline) Response at Week 16 Enrollment: 567 (ACTUAL) Lead Sponsor: UCB Biopharma SRL Start: 2017-12-06 | Primary Completion: 2019-01-08 Results posted: 2022-02-03