Inflammation Linked to Recurrence After AF-Related Stroke: Meta-Analysis
This meta-analysis of 10,080 patients reveals that elevated hsCRP is associated with recurrent MACEs in AF patients (aRR 1.14, 95% CI 1.04-1.25) and non-AF patients (aRR 1.08, 95% CI 1.03-1.13). No as…
Researchers studied how inflammation affects the risk of having another stroke after a first one related to heart rhythm issues. They found that inflammation is linked to a higher chance of serious he…
Angiography-derived FFR reduces perioperative events in CABG for valve surgery patients
In a multicentre RCT with 793 patients, physiologically guided CABG using angiography-derived FFR significantly reduced the composite perioperative outcome (RR 0.58, 95% CI 0.38-0.89, p=0.011) compare…
Researchers studied two ways to guide heart surgery for patients needing valve repair and found one method led to fewer complications. This suggests a more tailored approach could be better for patien…
Microvascular Resistance Reserve Predicts CAD Outcomes: HR 0.75 per Unit Increase
A meta-analysis (n=3,186) found that higher microvascular resistance reserve (MRR) is linked to reduced adverse cardiovascular events in CAD patients (HR per unit increase: 0.75; 95% CI: 0.64-0.88). L…
Researchers studied a new measure called microvascular resistance reserve to see how it relates to heart risks. They found that higher levels of this measure are linked to a lower chance of serious he…
Early Aspirin Withdrawal Post-PCI Reduces Bleeding, No MI Increase with P2Y12 Monotherapy
Meta-analysis shows early aspirin withdrawal (≤3 months) post-PCI with ticagrelor/prasugrel reduces bleeding (HR=0.55, 95% CI [0.42, 0.71]; p<0.001) without increasing MI risk (HR=1.11, 95% CI [0.91, …
Researchers studied whether stopping aspirin early after heart procedures could reduce bleeding risks. They found that for certain patients, stopping aspirin within three months can lower bleeding wit…
UC-MSC Infusions Safe in HFrEF, Improve RV Volumes, No LVEF Change
The PRIME-HFrEF trial found that multi-dose UC-MSC infusions in HFrEF patients were safe, with no significant difference in SAEs between groups. UC-MSCs improved RVESV (P=0.033) but did not significan…
Researchers studied the safety of a stem cell treatment for heart failure. They found that while the treatment was generally safe, it may increase blood clotting risk.…