Monday, March 30, 2026
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Latest Research View all →
Pulmonology & Critical Care Phase II
Capmatinib shows efficacy in Chinese NSCLC patients with MET exon 14 skipping mutations Could a targeted pill help Chinese patients with a specific lung cancer mutation?
An open-label, multicenter phase II study evaluated capmatinib in 36 Chinese adult patients with advanced NSCLC harboring MET exon 14 skippi…
A study tested the drug capmatinib in Chinese adults with advanced lung cancer driven by a specific MET gene mutation. The goal was to see i…
Nephrology Phase II
CFZ533 vs Tacrolimus in Kidney Transplant: Phase 2 Study Terminated After Interim Analysis Did a new drug for kidney transplant patients work better than standard treatment?
A Phase 2 study comparing the anti-CD40 monoclonal antibody CFZ533 to tacrolimus for preventing organ rejection in kidney transplant recipie…
A five-year study testing a new drug called CFZ533 against standard tacrolimus therapy in kidney transplant patients was stopped early. The …
OB/GYN & Women's Health Phase II
Letrozole reduces Ki67 in postmenopausal ER+/HER2- breast cancer after 7-30 days pre-surgery Can a short course of letrozole before surgery help shrink hormone-sensitive breast cancer?
A phase 2 trial of 61 postmenopausal women with ER+/HER2- operable breast cancer evaluated a 7- to 30-day preoperative course of letrozole 2…
For postmenopausal women with a common type of operable breast cancer, taking the drug letrozole for just 1-4 weeks before surgery may help …
OB/GYN & Women's Health Phase II
Phase II trial of cyclophosphamide, paclitaxel, trastuzumab in stage I-II HER2+ breast cancer completes with 20 patients Can a shorter, more intense chemo regimen help prevent early-stage HER2-positive breast cancer from returning?
A phase II trial evaluated a dose-dense regimen of cyclophosphamide, paclitaxel, and trastuzumab after surgery in 20 patients with stage I-I…
For women with early-stage HER2-positive breast cancer, a key question is whether a shorter, more intense chemotherapy schedule after surger…
OB/GYN & Women's Health Phase II
Phase II trial tests induction chemo with carboplatin, paclitaxel, lapatinib before transoral surgery in SCCHN Can a gentler, three-part treatment plan reduce side effects for head and neck cancer?
A single-arm phase II trial enrolled 40 previously untreated patients with SCCHN amenable to transoral surgery. Treatment involved 6 weeks o…
A study tested a new, three-part treatment plan for head and neck cancer that aims to be less toxic. The approach uses chemotherapy first, f…
Cardiology Phase II
Phase 2 pilot study evaluates ticagrelor monotherapy safety after stenting for acute MI Can a single blood thinner prevent heart attacks after stent placement?
A single-center, single-arm, prospective phase II pilot study of 200 patients assessed the initial safety of ticagrelor monotherapy after co…
Doctors are testing whether ticagrelor alone is safe enough to prevent dangerous heart complications after a stent is placed for a heart att…
Cardiology Phase IV
Phase 4 study evaluates nitroglycerin's effects on stroke volume in 21 AHF patients Can a common heart drug help people with acute heart failure breathe easier?
A Phase 4 study enrolled 21 patients with acute heart failure to evaluate the effects of nitroglycerin on stroke volume. The study aimed to …
When your heart suddenly can't pump well, fluid builds up and makes breathing a struggle. This study looked at whether nitroglycerin—a drug …
Cardiology Phase III
Phase 3 trial of milvexian for ACS prevention completes enrollment Can a new drug help prevent heart attacks and strokes after a serious heart event?
The LIBERATE trial, a Phase 3 study, has completed enrollment of 14,194 participants with a recent acute coronary syndrome to evaluate if mi…
A large study tested whether adding a new drug called milvexian to standard care could better protect people who recently had a serious hear…
Cardiology Phase II
Phase 2a trial of DFV890 and MAS825 for inflammation in CHD/CHIP patients completes with 31 participants Can two experimental drugs calm the dangerous inflammation linked to heart disease and a blood condition called CHIP?
A Phase 2a, multi-center, randomized, placebo-controlled, blinded study evaluated the efficacy, safety, and tolerability of DFV890 (oral dai…
Scientists tested two new drugs, DFV890 and MAS825, to see if they could lower key inflammation markers in people with both heart disease an…
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Outdoor time >120 min/day shows limited myopia protection in premyopic children Does playing outside protect kids' eyesight? For some children, it might not be enough.
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02
ZigZag CTG pattern in labor linked to higher risk of operative delivery, low pH, and late decelerations What does a 'zigzag' heart rate pattern during labor mean for your baby? New research finds concerning links.
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03
Post-mortem MRI shows 96% specificity, 76% sensitivity for cardiac anomalies in fetal/perinatal deaths Can a scan replace an autopsy for grieving parents? New research shows promise for detecting heart problems in stillborn babies.
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04
AAV9 gene therapy shows biochemical improvement, stable motor scores in GM1 gangliosidosis phase 1-2 trial Can gene therapy slow a rare, fatal childhood brain disease? Early trial shows some signs it might.
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05
Release of Wolbachia-infected male mosquitoes reduced dengue risk by 71-72% in Singapore trial Can releasing special male mosquitoes stop dengue? A trial in Singapore shows promising results.
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