Tuesday, March 31, 2026
Case report: Liver transplant recipient on dialysis for over 10 months recovered kidney function
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Case report: Liver transplant recipient on dialysis for over 10 months recovered kidney function

Key Takeaway
Note: Kidney recovery after >10 months of dialysis post-liver transplant is reported in a single case; likelihood is undefined.

A case report describes a single liver transplant recipient with pre-transplantation acute kidney injury attributed to hepatorenal syndrome with or without acute tubular necrosis. The patient was on maintenance dialysis. The intervention was liver transplantation; no comparator was reported. The primary outcome was kidney function recovery. The main result was that the single patient recovered kidney function after more than 10 months on dialysis. No effect size, p-value, or confidence interval was reported. Safety and tolerability data were not reported. Key limitations include the nature of the evidence: this is a single case report. The study design precludes establishing causation, and generalizability is extremely limited. The incidence and likelihood of kidney recovery in this population remain undefined. Practice relevance is highly restrained. This observation suggests that recovery after prolonged dialysis is possible in rare instances, but it does not inform the probability of such an event. Clinicians should recognize this as a very low-certainty, anecdotal report. Dependence on dialysis for more than 6 months has been suggested to diminish the likelihood of recovery, which contrasts with this finding and underscores the uncertainty.

View Original Abstract ↓
The incidence and likelihood of kidney function recovery in liver transplant recipients with acute kidney injury (AKI) due to hepatorenal syndrome (HRS) or acute tubular necrosis (ATN) requiring maintenance dialysis remain undefined. Nonetheless, it has been suggested that dependence on dialysis for more than 6 months diminishes the likelihood of renal function recovery. We report a liver transplant recipient with pre-transplantation AKI attributed to HRS with or without ATN who recovered kidney function after more than 10 months on dialysis.