Tuesday, March 31, 2026
FDA approves a new drug called Marinol to help with AIDS-related weight loss and chemotherapy nausea.
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FDA approves a new drug called Marinol to help with AIDS-related weight loss and chemotherapy nausea.

Plain Language Summary
What this means for you:
This is a new FDA-approved option for specific, severe cases of weight loss in AIDS and hard-to-treat chemo nausea.

The U.S. Food and Drug Administration (FDA) has approved a new prescription medicine called Marinol. Its active ingredient is dronabinol, which is a type of cannabinoid. The drug is approved to treat two specific problems in adults. First, it is for treating a lack of appetite and the serious weight loss that can happen in people with AIDS. Second, it is for managing the nausea and vomiting caused by cancer chemotherapy, but only for patients whose nausea has not gotten better enough with standard anti-nausea treatments.

This approval is important because it gives doctors another tool to help patients who are struggling with these challenging side effects of their illnesses or treatments. The FDA based its decision on clinical studies that showed Marinol was effective for these specific groups of people. The dose a patient takes is different depending on whether it is for AIDS-related weight loss or for chemotherapy nausea, and doctors will adjust it carefully.

It is important to know that Marinol is not for everyone. It is specifically for the two conditions mentioned and for patients who meet certain criteria. Like all medicines, it can have side effects, which can include effects on the brain and nervous system. The approval means the drug has been found safe and effective for its intended uses, but it is still a powerful prescription medication.

If you or someone you care for has AIDS with severe weight loss or is dealing with chemotherapy nausea that other treatments haven't helped, this news might be relevant. The most important step is to have a conversation with the treating doctor. They can explain if Marinol could be a suitable option based on an individual's specific health situation and overall care plan.

What this means for you:
This is a new FDA-approved option for specific, severe cases of weight loss in AIDS and hard-to-treat chemo nausea.
Read the Full Clinical Summary →
View Original Abstract ↓
1 INDICATIONS & USAGE MARINOL is indicated in adults for the treatment of: • anorexia associated with weight loss in patients with Acquired Immune Deficiency Syndrome (AIDS). • nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments. MARINOL is a cannabinoid indicated in adults for the treatment of: • Anorexia associated with weight loss in patients with AIDS. (1) • Nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments.